Security-First Design Principles for Multi-Tenant Cloud-Native Application Frameworks in Regulated Industries

Abstract

In regulated industries, securing multi-tenant cloud-native application frameworks demands rigorous attention to design principles that prioritize security from inception. This paper explores critical security-first principles such as zero trust, policy-driven architecture, tenant isolation, secure software supply chain, and compliance integration. Through literature analysis and current trends, it also identifies practical architectures and discusses key implementation challenges. A data-driven overview illustrates how adoption varies across sectors like healthcare and finance. This study contributes to establishing a secure, compliant, and scalable foundation for cloud-native applications in multi-tenant contexts.